Eczema, also known as atopic dermatitis, is a chronic skin condition characterized by red, itchy, and inflamed skin. It is a common condition that affects people of all ages, but is most commonly diagnosed in children. Eczema can have a significant impact on an individual's quality of life, as the itching and inflammation can be debilitating and the condition can be difficult to manage.
Unfortunately, there is no cure for eczema, but it can be managed with a combination of treatment options. The goal of eczema treatment is to reduce inflammation, relieve symptoms, and prevent future outbreaks.
The first line of treatment for eczema is the use of moisturizers. Moisturizers help to hydrate the skin and reduce itching and dryness. They should be applied to the skin immediately after bathing, when the skin is still damp, in order to lock in moisture.
Topical corticosteroids are also commonly used to reduce inflammation and relieve symptoms. They are available in various strengths and can be applied to the affected area of the skin. However, they should be used under the guidance of a healthcare professional as they can have side effects if used excessively.
There is another topical medication called Protopic (tacrolimus) which is an immunosuppressant medication that works by reducing inflammation in the skin. It is applied directly to the affected area of the skin and is approved to treat moderate-to-severe eczema in adults and children.
Oral medications, such as antihistamines, may be prescribed to relieve itching and help with sleep disturbances. Antibiotics may be prescribed if a secondary bacterial infection is present.
Light therapy, also known as phototherapy, can be used to reduce inflammation and improve the appearance of the skin. It involves exposing the skin to controlled doses of ultraviolet (UV) light.
In addition to the traditional treatments for eczema mentioned earlier, biologics are a newer class of medications that have been developed to specifically target the underlying causes of eczema. Biologics are usually administered via injection or infusion, and they work by targeting specific proteins or cells that are involved in the inflammatory process.
One example of a biologic medication is dupilumab (Dupixent). Dupilumab is a monoclonal antibody that blocks the action of interleukin-4 (IL-4) and interleukin-13 (IL-13), two proteins that play a key role in the development of eczema. It is approved for the treatment of moderate-to-severe atopic dermatitis in adults who are not adequately controlled by topical medications or when those are not advisable. Tralokinumab (Adbry) is another injectable approved for treating eczema. It is similar to Dupilumab, but targets only IL-13.
Another example of a biologic medication is crisaborole (Eucrisa), which is a phosphodiesterase 4 (PDE4) inhibitor that works by reducing inflammation in the skin. It is approved for the treatment of mild-to-moderate eczema in children and adults.
Finally, ruxolitinib (Jakafi) is a medication that targets the JAK1 and JAK2 proteins which are involved in the inflammatory process. This medication is approved to treat moderate-to-severe eczema in adults who are not responding to traditional treatments.
In addition to medical treatments, lifestyle changes can also help to manage eczema. This includes avoiding triggers, such as certain fabrics, soaps, and detergents, that can irritate the skin. It's also important to maintain a healthy diet and to manage stress, as they can both affect the skin.
It's important to work closely with a healthcare professional to develop an individualized treatment plan that addresses the specific needs and triggers of the patient. The treatment plan may need to be adjusted over time as the patient's symptoms and triggers change.
In conclusion, eczema is a chronic skin condition that can be managed with a combination of treatment options. The goal of eczema treatment is to reduce inflammation, relieve symptoms, and prevent future outbreaks. Moisturizers, topical corticosteroids, oral medications, light therapy, and lifestyle changes can all be used to manage eczema. It's important to work closely with a healthcare professional to develop an individualized treatment plan that addresses the specific needs and triggers of the patient.
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